TABLE 1.
Performance of E-MTD, by specimen and by patient, after initial testinga
| Parameterb | E-MTD result | No. with MTBC culture result of:
|
Sensitivity (%) | Specificity (%) | PPV (%)c | NPV (%)d | |
|---|---|---|---|---|---|---|---|
| Positive | Negative | ||||||
| By specimen | |||||||
| Overall | Positive | 28 | 12 | 77.8 | 98.8 | 70.0 | 99.2 |
| Negative | 8 | 956 | |||||
| AFB+ | Positive | 13 | 2 | 100 | 77.8 | 86.7 | 100 |
| Negative | 0 | 7 | |||||
| AFB− | Positive | 15 | 10 | 65.2 | 99.0 | 60.0 | 99.2 |
| Negative | 8 | 949 | |||||
| By patient | |||||||
| Overall | Positive | 20 | 6 | 80.0 | 98.7 | 76.9 | 98.9 |
| Negative | 5 | 458 | |||||
| AFB+ | Positive | 10 | 1 | 100 | 83.3 | 90.9 | 100 |
| Negative | 0 | 5 | |||||
| AFB− | Positive | 10 | 5 | 66.7 | 98.9 | 66.7 | 98.9 |
| Negative | 5 | 453 | |||||
Before discrepancies were resolved.
AFB+, positive smear for AFB; AFB−, negative smear for AFB.
PPV, positive predictive value.
NPV, negative predictive value.