TABLE 3.

Performance of E-MTD, by patient, after resolution of discrepancies and modification of interpretive results

Parametera	E-MTD result	No. of patients with MTBC culture result of:		Sensitivity (%)	Specificity (%)	PPV (%)b	NPV (%)c
		Positive	Negative
Resolved
Overall	Positive	20	4	90.9	99.1	83.3	99.6
	Negative	2	460
AFB+	Positive	10	0	100	100	100	100
	Negative	0	5
AFB−	Positive	10	4	83.3	99.1	71.4	99.6
	Negative	2	455
With expanded equivocal zone
Overall	Positive	20	1	90.9	99.8	95.2	99.6
	Negative	2	463
AFB−	Positive	10	1	83.3	99.8	90.9	99.6
	Negative	2	458

^aAFB⁺, positive smear for AFB; AFB⁻, negative smear for AFB. Data and performance characteristics for smear-positive patients are the same for both categories. For the second category, the equivocal zone was changed from 30,000 to 500,000 RLU to 30,000 to 1 million RLU. 

^bPPV, positive predictive value. 

^cNPV, negative predictive value.