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. 2021 Sep 15;12:740517. doi: 10.3389/fimmu.2021.740517

Table 3.

Factor-specific incidences of adverse reactions to low-dose IVIG*.

Patient basis (n=360) Infusion basis (n=1192)
Adverse reaction Adverse reaction
No Yes p value No Yes p value
Gender, n (%)
Male 211 (99.1) 2 (0.9) 680 (99.6) 3 (0.4)
Female 145 (98.7) 2 (1.3) 1.00 507 (99.6) 2 (0.4) 1.00
Age, n (%)
< 15 years 69 (97.2) 2 (2.8) 181 (97.2) 3 (1.6)
≥ 15 years 287 (99.3) 2 (0.7) 0.245 1006 (99.3) 2 (0.2) 0.025
IVIG doses (average, g/kg BW) 0.4 1.4 0.395 0.16 0.19 0.564
Indication, n (%)
Hypogammaglobulinaemia 63 (98.4) 1 (1.6) 286 (99.4) 2 (0.6)
Sepsis 293 (99.0) 3 (1.0) 901 (99.7) 3 (0.3)

*The low-dose IVIG is less than 0.7 g/kg body weight per course.

The values indicate the cumulative doses from multiple treatment of IVIG on one patient.

BW, body weight of patient.