Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 15;11:703461. doi: 10.3389/fonc.2021.703461

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Wang, Dong, Wu, Wang, Shi and Zheng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Pan-normal tissue-enriched circRNAs. (A) Heatmap illustrating the expression of pan-normal tissue-enriched circRNAs selected by LASSO regularization analysis among the top 10%, top 10%–20%, and top 20%–30% stably expressed circRNAs. Turquoise: top 10%; yellow: top 10%–20%; gray: top 20%–30%. Red: pan-cancer tissues; blue: pan-normal tissues; rainbow: tissue types. (B) Receiver operating characteristic curve showing the sensitivity of pan-normal tissue-enriched circRNAs to classify pan-cancer and pan-normal tissues via the support vector machine. The top 10%, top 10%–20%, and top 20%–30% of stably expressed circRNAs were separately analyzed. Blue: training set; red: validation set. (C) Functional enrichment of the host genes of pan-normal tissue-enriched circRNAs among the top 10% of stably expressed circRNAs.