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. 2021 Sep 15;12:730751. doi: 10.3389/fphar.2021.730751

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Copyright © 2021 Hu, Zhang, Chen, Shen, Jiang, Sun and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Drugs targeting lipid metabolism. In this figure, we presented related drugs, which were listed in Table 1, in the boxes and linked them to the targets of lipid metabolism including lipid uptake, lipolysis, fatty acid oxidation, lipid synthesis, lipid desaturation, the mevalonate pathway and lipid peroxidation. (ACLY, ATP citrate lyase; ACC, acetyl-CoA carboxylase; CAA, cancer-associated adipocytes; FA, fatty acid; FAO, fatty acid oxidation; FASN, fatty acid synthase; CD36, cluster of differentiation 36; LD, lipid droplet; CPT1, carnitine palmitoyltransferase-1; MUFA, monounsaturated fatty acid; MSC, mesenchymal stem cell; SCD1, stearoyl-CoA desaturase 1; TME, tumor microenvironment; LPO, lethal lipid peroxides).