Table 2.

Potential biomarkers of disease severity in COVID-19.

Analytes	Changes	Role	Ref
IL-1, IL-2, IL-6, TNF-a, G-CSF, GM-CSF, IFN-γ	Increase	Cytokine storm biomarker	(102)
CD3+, CD4+, CD8+, B cells, NK cells	Decrease	Clinical Hematological biomarker	(103)
CK, CK-MB, CRP, Ferritin, LDH, BUN, Creatinine, cTnI, AST, ALT, Total bilirubin	Increase	Clinical Biochemical biomarker	(104)

IL, interleukin; TNF-a, tumor necrosis factor; GM-CSF, granulocyte-macrophage colony-stimulating factor; G-CSF, granulocyte colony-stimulating factor; IFN-γ, interferon gamma; NK, natural killer; CK, creatine kinase; LDH, lactate dehydrogenase; BUN, blood urea nitrogen; cTnI, cardiac troponin I; AST, aspartate aminotransferase; ALT, alanine aminotransferase.