Figure 2.

Box plots showing the percent change from baseline to week 24 regarding the renal function, liver function, and creatine kinase demonstrated by the Mann-Whitney U test. A p value of 0.05 was considered to be significant. Boxes show the medians and interquartile ranges with the lowest and highest values being shown above and below each box. The figure illustrates the findings of safety analyses, which found no significant differences between the CKD and non-CKD groups. Cre: creatinine, eGFR: estimated glomerular filtration rate, ALT: alanine aminotransferase, γGT: γ-glutamyl transferase, CK: creatine kinase