Table 4.
Comparison of Baseline Laboratory Data between the CKD and Non-CKD Groups
| CKD (n=54) | non-CKD (n=72) | p value | ||||
|---|---|---|---|---|---|---|
| Efficacy parameters | ||||||
| TC (mg/dL) | 184.5 [161.5, 221.5] | 199.5 [164.3, 222.0] | 0.415 | |||
| LDL-C (mg/dL) | 96.5 [74.5, 129.0] | 109.5 [86.3, 131.0] | 0.441 | |||
| non-HDL-C (mg/dL) | 144.5 [116.0, 175.8] | 152.5 [121.0, 178.8] | 0.751 | |||
| TG (mg/dL) | 260.0 [200.8, 383.0] | 273.0 [155.5, 525.5] | 0.745 | |||
| HDL-C (mg/dL) | 42.5 [35.0, 48.0] | 46.0 [37.3, 53.0] | 0.079 | |||
| Safety parameters | ||||||
| BUN (mg/dL) | 19.0 [16.0, 23.6] | 14.4 [11.0, 18.0] | <0.001 | |||
| Cre (mg/dL) | 1.07 [0.94, 1.29] | 0.74 [0.62, 0.89] | <0.001 | |||
| eGFR (mL/min/1.73m2) | 47.6 [41.7, 55.8] | 73.5 [66.3, 86.3] | <0.001 | |||
| ALT (IU/L) | 23.0 [17.0, 35.3] | 27.0 [18.3, 40.5] | 0.272 | |||
| γGT (IU/L) | 41.5 [24.3, 52.5] | 41.0 [29.0, 82.0] | 0.909 | |||
| CK (U/L) | 79.0 [59.5, 101.0] | 85.5 [68.0, 114.0] | 0.936 |
Data are presented as the median [25%, 75%]. p<0.05 vs. non-CKD by Mann-Whitney U test.
CKD: chronic kidney disease, TC: total cholesterol, LDL-C: low-density lipoprotein cholesterol, non-HDL-C: non-high-density lipoprotein cholesterol, TG: triglycerides, HDL-C: high-density lipoprotein cholesterol, BUN: blood urea nitrogen, Cre: creatinine, eGFR: estimated glomerular filtration rate, ALT: alanine aminotransferase, γGT: γ-glutamyl transferase, CK: creatine kinase