Important serum metabolites identified for discrimination of cognitively affected and healthy individuals. Boxplots representation with medians, interquartile ranges, and whiskers for minimum and maximum measurements. Significance is indicated by ** <0.01 and * <0.05. Allopurinol riboside, inosine, 4-pyridoxic acid, and guanosine were measured by LC-MS, while valine and histidine were measured by NMR.