E faecalis up-regulates expression of a putative PTS operon, OG1RF_11616-11610, during experimental colitis. (A) Organization of open reading frames in the putative PTS operon, OG1RF_11616-11610, in E faecalis. NCBI annotations are indicated below, and fold change (Il10-/- vs WT mice from Figure 1) is indicated above, each open reading frame. (B) E faecalis OG1RF_116616 mRNA abundance in cecal content from WT and Il10-/- mice colonized with the 8 bacterial strains as in Figure 1 for 5–10 weeks (n = 4–6 mice/group, data presented as means ± SD, ∗P < .05 Il10-/- vs WT, Student t test).