Table 4.
Binomial univariate and multivariate logistic regressions (Triple-negative breast cancer vs Non-triple-negative breast cancer)
| TNBC vs Non-TNBC |
Univariate
|
Multivariate (AUC = 0.853)
|
|||||
|
|
|
P
|
OR
|
CI
|
P
|
OR
|
CI
|
| Posterior acoustic features1 | Enhancement | b | 5.08 | (1.808 18.201) | a | 4.77 | (1.556 18.291) |
| Margins2 | Spiculated | a | 0.43 | (0.179 0.951) | Not significant | ||
| Circumscribed | c | 11.00 | (3.712 37.166) | b | 8.24 | (2.151 38.923) | |
| Size | Large > 20 mm | c | 13.2 | (5.152 44.845) | c | 10.5 | (3.792 38.436) |
| Axillary node metastasis | Yes | b | 2.52 | (1.247 4.988) | Not significant | ||
| Adler’s Index | High | a | 2.12 | (1.104 4.020) | Not significant | ||
| aScreening | Yes | d | 0.003 | (0.000 0.222) | d | 0.004 | (0.000 0.452) |
| aInteraction term | Screen × unit size | d | 1.17 | (1.003 1.505) | d | 1.16 | (1.001 1.430) |
1
Mixed posterior acoustic features were set as the baseline with OR = 1.
2
Microlobulated ultrasound margins were set as the baseline with OR = 1.
a
Significant at the 0.001 level.
b
Significant at the 0.01 level.
c
Significant at the 0.05 level.
d
Significant at the 0.10 level.
Area under the receiver operating characteristic curve for multivariate regression on posterior acoustic features, ultrasound margins, and size (large or small). AUC: Area under the receiver operating characteristic curve; TNBC: Triple-negative breast cancer.