Fig. 5.

A & B). Accessing potential role of glycosylation in cross-reactivity of Anti-SARS-C0V2 polyclonal antibodies: Cross-reactivity of spike immunized mice sera was tested for gp120 and gp140 protein ELISA and in Western blot analysis. The spike immunized mice sera specifically bound to the gp140 protein and did not cross-react with the gp120 protein. The same blot was restriped and blotted with PGT121 mAb to insure equal loading of experimental proteins. C). The extent of binding of spike and RBD immunized mice sera was tested for HIV-1 MPER peptide.