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. 2021 Sep 28;2(10):100421. doi: 10.1016/j.xcrm.2021.100421

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© 2021.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Comparison of SARS-CoV-2 Spike mRNA epithelial expression by clinical comorbidities

(A) SARS-CoV-2 intensity (left) and positive areas (right) are statistically significantly higher among smokers (current/former) (n = 6) compared with non-smokers (n = 14) (two-tailed Mann-Whitney test, ∗∗p = 0.0033 and ∗∗p = 0.0032, respectively).

(B) No statistically significant differences were seen in SARS-CoV-2 intensity (left) or positive areas (right) among individuals with or without pre-existing type II diabetes mellitus (n = 10 and n = 14, respectively) (two-tailed Mann-Whitney test, p = 0.4716 and p = 0.7521, respectively).

(C) No statistically significant differences were seen in SARS-CoV-2 intensity (left) or positive areas (right) among individuals with or without pre-existing hypertension (n = 15 and n = 8, respectively) (two-tailed Mann-Whitney test, p = 0.7284 and p = 0.9246, respectively).

See also Figure S5.