Table V.
Top 30 downregulated genes (Test group vs control group).
| Gene_Name | Locus | Fold_Change | p_value |
|---|---|---|---|
| MMP3 | chr11:102706532 to 102714534 | 0.014042996 | 1.50127E-05 |
| MMP1 | chr11:102660651 to 102668891 | 0.027904979 | 0.001006739 |
| CHI3L2 | chr1:111743393 to 111786062 | 0.029793628 | 2.76304E-06 |
| AMTN | chr4:71384257 to 71398459 | 0.031193966 | 0.003623208 |
| CHI3L1 | chr1:203148059 to 203155877 | 0.033144309 | 2.27443E-05 |
| MMP13 | chr11:102813724 to 102826463 | 0.034096806 | 0.000188804 |
| SPP1 | chr4:88896802 to 88904578 | 0.045835679 | 0.000167266 |
| CSN1S1 | chr4:70796799 to 70812292 | 0.047230259 | 0.014938042 |
| RPS4Y1 | chrY:2709527 to 2800041 | 0.059853056 | 0.004809868 |
| MT1G | chr16:56700643 to 56701977 | 0.069314334 | 1.87297E-05 |
| MMP9 | chr20:44637547 to 44645200 | 0.074788099 | 0.011522448 |
| CCL18 | chr17:34391640 to 34399392 | 0.101491719 | 0.012068675 |
| RGS1 | chr1:192544857 to 192549161 | 0.126175485 | 0.001007045 |
| POSTN | chr13:38136720 to 38172981 | 0.131198599 | 0.000195461 |
| TREM1 | chr6:41235664 to 41254457 | 0.135158542 | 0.000603453 |
| LRRC15 | chr3:194075976 to 194090472 | 0.154291164 | 0.005223527 |
| LBP | chr20:36974759 to 37005665 | 0.160979678 | 0.020468865 |
| DDX3Y | chrY:15016019 to 15032390 | 0.166462769 | 0.005450236 |
| CPXM1 | chr20:2774715 to 2781283 | 0.170064956 | 0.006423577 |
| AL645922.1 | chr6:31895475 to 31919825 | 0.171054864 | 0.019080061 |
| S100A9 | chr1:153330330 to 153333503 | 0.17538335 | 0.023651438 |
| CA9 | chr9:35673853 to 35681156 | 0.175724451 | 0.009030186 |
| HBA1 | chr16:226679 to 227521 | 0.177789082 | 0.031770506 |
| ARL4C | chr2:235401685 to 235405697 | 0.19074171 | 0.001131891 |
| MT1F | chr16:56691606 to 56694610 | 0.193573717 | 4.55998E-05 |
| ANGPTL4 | chr19:8428173 to 8439257 | 0.193679538 | 0.000326219 |
| TMIGD3 | chr1:112025970 to 112106584 | 0.197980927 | 0.004255273 |
| HBB | chr11:5246694 to 5250625 | 0.202378973 | 0.030887531 |
| CXCL8 | chr4:74606223 to 74609433 | 0.207242113 | 0.003540663 |
| ALPL | chr1:21835865 to 21904905 | 0.213662582 | 0.00609762 |
ALPL, alkaline phosphatase, biomineralization associated; AMTN, amelotin; ANGPTL4, angiopoietin like 4; ARL4C, ADP ribosylation factor like GTPase 4C; CA9, carbonic anhydrase 9; CCL18, C-C motif chemokine ligand 18; CHI3L1, chitinase 3 like 1; CPXM1, carboxypeptidase X, M14 family member 1; CSN1S1, casein alpha S1; CXCL8, C-X-C motif chemokine ligand 8; DDX3Y, DEAD-Box Helicase 3 Y-Linked; HBA1, haemoglobin subunit alpha 1; HBB, haemoglobin subunit beta; LBP, lipopolysaccharide binding protein; LRRC15, leucine rich repeat containing 15; MMP, matrix metalloproteinase; MT1F, metallothionein 1F; MT1G, metallothionein 1G; POSTN, periostin; RGS1, regulator of G protein signaling 1; RPS4Y1, ribosomal protein S4 Y-Linked 1; S100A9, S100 calcium binding protein A9; SPP1, secreted phosphoprotein 1; TMIGD3, transmembrane and immunoglobulin domain containing 3; TREM1, triggering receptor expressed on myeloid cells 1.