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. 2021 Sep 27;10(9):619–628. doi: 10.1302/2046-3758.109.BJR-2021-0016.R1

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© 2021 Author(s) et al.

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Fig. 6 — Expression of mineralization-related genes in osteoblasts from patients with osteonecrosis of the femoral head (ONFH). Bone gamma-carboxyglutamate protein (BGLAP), integrin binding sialoprotein (IBSP), and secreted phosphoprotein 1 (SPP1) messenger RNA (mRNA) levels in osteoblasts obtained from the intertrochanteric region (IT) of patients with osteoarthritis (OA) or ONFH and from the femoral head of patients with ONFH, and cultured in osteogenic medium for 18 days. The data were normalized relative to those measured in osteoblasts from IT-OA, which were given an arbitrary value of 1. *p < 0.05 between the indicated conditions, Mann–Whitney U test and paired Wilcoxon test.