Table 3.
Primary and key secondary outcomes
| CT computed angiography and standard of care (n=877) | Standard of care only (n=871) | Estimate | Hazard ratio (95% CI) | P value* | |
|---|---|---|---|---|---|
| Primary outcome | |||||
| All cause death or non-fatal myocardial infarction (type 1 or 4b) | 51 (5.8) |
53 (6.1) |
Unadjusted | 0.95 (0.65 to 1.40) | 0.79 |
| Adjusted | 0.91 (0.62 to 1.35) | 0.65 | |||
| Secondary outcomes | |||||
| Death from coronary heart disease or non-fatal myocardial infarction | 47 (5.4) |
45 (5.2) |
Unadjusted | 1.03 (0.69 to 1.55) | 0.88 |
| Adjusted | 1.02 (0.67 to 1.53) | 0.94 | |||
| Death from cardiovascular disease or non-fatal myocardial infarction | 48 (5.5) |
46 (5.3) |
Unadjusted | 1.03 (0.69 to 1.54) | 0.88 |
| Adjusted | 1.01 (0.68 to 1.52) | 0.95 | |||
| Non-fatal myocardial infarction |
39 (4.4) |
40 (4.6) |
Unadjusted | 0.96 (0.62 to 1.50) | 0.87 |
| Adjusted | 0.95 (0.61 to 1.47) | 0.81 | |||
| Death from coronary heart disease |
11 (1.3) |
6 (0.7) |
Unadjusted | 1.82 (0.67 to 4.92) | 0.24 |
| Adjusted | 1.78 (0.66 to 4.82) | 0.26 | |||
| Death from cardiovascular death |
12 (1.4) |
8 (0.9) |
Unadjusted | 1.49 (0.61 to 3.64) | 0.38 |
| Adjusted | 1.39 (0.57 to 3.42) | 0.47 | |||
| All cause death |
19 (2.2) |
17 (2.0) |
Unadjusted | 1.11 (0.58 to 2.13) | 0.76 |
| Adjusted | 1.03 (0.53 to 1.99) | 0.94 | |||
Data are number (%) unless stated otherwise. Adjusted hazard ratios are from models adjusting for study site, GRACE (global registry of acute coronary events) score, and previous coronary heart disease.
CT=computed tomography.
*
Nominal P values provided for secondary outcomes given the primary outcome was not statistically significant.