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. Author manuscript; available in PMC: 2021 Sep 29.
Published in final edited form as: FASEB J. 2020 Aug 3;34(9):12847–12859. doi: 10.1096/fj.202000713RR

Figure 3.

Figure 3

Load-driven alterations in urinary volatile organic compounds (VOCs). Of note, PCA = principal component axis. The single and double asterisks indicate p < 0.05 and p < 0.01, respectively. (A) Hierarchical clustergram for the normal, placebo, and loaded groups, including 22 VOCs. (B&C) Principal component plots for the urine samples and 22 VOCs, respectively. (D) Mevalonate pathway leading to cholesterol synthesis including 5 VOCs (alpha/beta-farnesene, linalool, isoprenul alcohol, and beta-pinene) that were enriched in the placebo group.