Table 1.
Human Leucocyte Antigen (HLA)alleles associated with autoimmune hepatitis (AIH).
| HLA allele | Association | Population | Study |
|---|---|---|---|
| DRB1*0301 and DRB1*0401 | AIH-1 | European, North Americans | Mackay et al., 1980 [21] Krawitt et al., 1987 [22] Donaldson et al., 1991 [23] Seki et al., 1990 [24] Doherty et al., 1994 [26] Strettel et al., 1997 [27] Boer et al., 2014 [28] Donaldson et al., 2002 [29] |
| DRB1*0404, DRB1*0405 and DRB1*1301 | AIH-1 | Latin Americans Japanese |
Umemura et al., 2014 [25] Pando et al., 1999 [34] Czaja et al., 2002 [35] Czaja et al., 2008 [36] Goldberg et al., 2001 [37] Fortes et al., 2007 [38] Fainboin et al., 1994 [39] Furumoto et al., 2015 [42] Seki et al., 1992 [41] |
| DRB1*0802 and DRB1*0803 | AIH-1 | Japanese | Oka et al., 2017 [43] |
| DRB1*13 and DRB1*14 | AIH-1 | Indian, Iranian | Amarapurkar et al., 2003 [44] Baharlu et al., 2016 [45] |
| DRB1*07 and DRB1*03 | AIH-2 | European | Ma et al., 2006 [43] Underhill et al., 2002 [46] |
| DRB1*15 | AIH-2 | Egyptian | Elfaramawy et al., 2010 [48] |
Abbreviations: HLA, human leucocyte antigen; AIH, autoimmune hepatitis.