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. 2021 Aug 31;20:100141. doi: 10.1016/j.mcpro.2021.100141

Fig. 1.

Fig. 1

The expression of MALAT1 in HCC tumor tissues and cell lines.A, comparison of the expression of MALAT1 between tumor and nontumor samples from the TCGA-LIHC (Liver Hepatocellular Carcinoma) transcriptomics data. Transcripts Per Million (TPM) values were used for quantification. Boxplot center lines = median, lower bound = 25% quantile, upper bound = 75% quantile, lower whisker = the smallest observation greater than or equal to the lower hinge −1.5 × interquartile range (IQR), upper whisker = the largest observation less than or equal to the upper hinge +1.5 × IQR. Wilcoxon rank-sum test was used for statistical analysis. B, relative levels of MALAT1 across seven HCC cell lines. Data represent mean ± s.d. C, interacting proteome network of MALAT1 involving in RNA splicing. The network was constructed by Cytoscape (version: 3.8.0). D, the workflow of the experimental approach employed in this study.