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. Author manuscript; available in PMC: 2022 Jun 1.
Published in final edited form as: Exp Cell Res. 2021 Mar 31;403(1):112581. doi: 10.1016/j.yexcr.2021.112581

Figure 1:

Figure 1:

Effects of IKK2 Inhibition on laser-induced CNV in mice.

In vivo fluorescent angiography in control animals (A) or animals treated with subconjunctival IMD-0354 (10 μg) (B) 5 days after laser CNV induction. Images were taken 60 seconds after the subcutaneous injection of fluorescein sodium. Arrows indicate fluorescein leakage areas. Ex vivo evaluation of the laser spot sizes in RCSC flat mounts in control (C) and IMD-0354-treated eyes (D). Quantitative analysis of laser CNV area in RCSC flat mounts (E). Statistical significance was determined using Student’s t-test. ***p < 0.001. n=5 (5 eyes, 15 CNV spots)