Table 2.
Univariate and multivariate logistic analysis of prognostic factors associated with vascular invasion
| Risks | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | |
| Age, n (%) | ||||
| ≤ 60 | Reference | Reference | ||
| > 60 | 0.46 (0.29, 0.74) | < 0.001 | 0.44 (0.27, 0.74) | 0.001 |
| Sex, n (%) | ||||
| Female | Reference | |||
| Male | 1.36 (0.8, 2.32) | 0.245 | ||
| Albumin, n (%) | ||||
| ≤ 40 | Reference | |||
| > 40 | 1.26 (0.88, 1.81) | 0.208 | ||
| TB, n (%) | ||||
| > 20 | Reference | |||
| ≤ 20 | 0.97 (0.53, 1.77) | 0.916 | ||
| AFP, n (%) | ||||
| ≤ 400 | Reference | Reference | ||
| > 400 | 2.3 (1.56, 3.4) | < 0.001 | 1.63 (1.06, 2.51) | 0.026 |
| Cirrhosis, n (%) | ||||
| No | Reference | |||
| Yes | 1.24 (0.79, 1.97) | 0.344 | ||
| Size, n (%) | ||||
| ≤ 5 | Reference | |||
| > 5 | 2.96 (2.04, 4.31) | < 0.001 | 2.15 (1.42, 3.24) | < 0.001 |
| Number, n (%) | ||||
| Solitary | Reference | Reference | ||
| Multiple | 1.68 (1.05, 2.68) | 0.032 | 1.44 (0.85, 2.41) | 0.175 |
| Tumor capsule, n (%) | ||||
| Absence | Reference | Reference | ||
| Presence | 1.79 (1.24, 2.59) | 0.002 | 1.64 (1.09, 2.47) | 0.018 |
| Differential, n (%) | ||||
| Good | Reference | Reference | ||
| Moderate/poor | 3.44 (2.35, 5.04) | < 0.001 | 2.90 (1.93, 4.36) | < 0.001 |
| BCLC, n (%) | ||||
| A | Reference | |||
| B | 2.95 (2.46, 3.43) | < 0.001 | 2.62 (2.21, 3.03) | < 0.001 |
| C | 3.02 (2.63, 3.72) | < 0.001 | 2.76 (2.33, 3.15) | < 0.001 |
| ALBI Grade, n (%) | ||||
| A | Reference | Reference | ||
| B | 1.95 (1.23, 2.67) | 0.003 | 1.44 (0.93, 2.21) | 0.1 |
| GGT/ALT | ||||
| ≤ 2.95 | Reference | Reference | ||
| > 2.95 | 1.96 (1.34, 2.87) | < 0.001 | 1.60 (1.05, 2.43) | 0.030 |
TB, Total Bilirubin; AFP, α-fetoprotein; BCLC, Barcelona Clinic Liver Cancer staging; ALBI grade, Albumin-Bilirubin Grade; GGT, γ-Glutamyl Transpeptidase; ALT, Alanine aminotransferase