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. 2021 Sep 28;20:197. doi: 10.1186/s12933-021-01374-8

Table 4.

Hazard ratios and 95% confidence intervals for hospitalization for heart failure, all-cause mortality and cardiovascular mortality in patients with previous heart failure according to FLI score

Model 1 Model 2 Model 3 Model 4
Events (n) HR 95% CI p value HR 95% CI p value HR 95% CI p value HR 95% CI p value
hHF
 FLI < 20 495 Ref. Ref. Ref. Ref.
 20 ≤ FLI < 60 677 1.059 0.943–1.189 0.334 1.123 0.982–1.283 0.090 1.113 0.973–1.272 0.118 1.040 0.909–1.190 0.567
 FLI ≥ 60 250 1.141 0.980–1.328 0.090 1.469 1.203–1.793 < 0.001 1.428 1.168–1.746 < 0.001 1.259 1.027–1.543 0.027
All-cause mortality
 FLI < 20 525 Ref. Ref. Ref. Ref.
 20 ≤ FLI < 60 563 0.823 0.730–0.926 0.001 1.151 1.001–1.325 0.049 1.141 0.991–1.313 0.067 1.054 0.915–1.215 0.466
 FLI ≥ 60 190 0.803 0.680–0-948 0.010 1.836 1.480–2.277  < 0.001 1.792 1.441–2.228 < 0.001 1.541 1.236–1.922 < 0.001
CV mortality
 FLI < 20 93 Ref. Ref. Ref. Ref.
 20 ≤ FLI < 60 114 0.942 0.717–1.239 0.671 1.355 0.982–1.870 0.064 1.338 0.968–1.850 0.077 1.210 0.874–1.675 0.250
 FLI ≥ 60 34 0.812 0.549–1.203 0.300 1.937 1.170–3.206 0.010 1.850 1.112–3.077 0.018 1.535 0.918–2.568 0.102

CI confidence interval, CV mortality cardiovascular mortality, HR hazard ratio, hHF hospitalized heart failure

Model 1: crude

Model 2: age, sex and body weight

Model 3: model 2 + alcohol drinking, smoking, regular exercise, and income status

Model 4: model 3 + hypertension, diabetes mellitus, dyslipidemia, and estimated glomerular filtration rate