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. 2022 Jan;192(1):112–120. doi: 10.1016/j.ajpath.2021.09.004

Figure 1.

Figure 1

Quantification of micro- and macrothrombosis in hearts of patients with COVID-19. A: The frequency of microthrombi per 20× field was quantified in controls and patients with COVID-19. Representative images of microthrombi composed of platelets and/or fibrin. B: The total numbers of macrothrombi per tissue section were counted by imaging whole tissue at 10× and dividing by tissue area. Representative images of macrothrombi composed of platelets and/or fibrin. C: Image of a megakaryocyte present in heart tissue. CD42b was used to identify platelets; ICAM-1 for vessels. Data represent means ± SEM. ∗∗P < 0.01, ∗∗∗P < 0.001. Scale bars: 50 μm (A and B, left images, and C); 100 μm (A and B, right images).