Table 1.
Patient Demographics and Clinical Information
COVID-19 patients (n = 7)∗ | Age | Sex | Cardiac history | Medications | Cause of death |
---|---|---|---|---|---|
Patient 1 | 94 | F | CAD | Remdesivir | Pneumonia |
Patient 2 | 65 | F | CAD, DVT, NSTEMI | Prednisone, Rivaroxaban | Pneumonia w/DAD leading to ARDS |
Patient 3 | 77 | M | None | Pneumonia and pulmonary thrombosis in setting of end stage renal disease | |
Patient 4 | 57 | M | None | Pneumonia leading to cardiac arrest, followed by shock | |
Patient 5 | 90 | M | CAD, stroke | Pneumonia w/DAD | |
Patient 6 | 68 | F | CAD, MI | Pneumonia in setting of CV disease and recent MI | |
Patient 7 | 50 | M | None | Bilnatumomab | Pneumonia w/DAD in setting of B cell ALL relapse |
Controls (n = 12) | |||||
Control 1 | 89 | M | CAD, stroke | Atherosclerotic and hypertensive CV disease | |
Control 2 | 47 | M | CAD, MI | CHF | |
Control 3 | 79 | M | Atrial Flutter, CKD | CHF | |
Control 4 | 58 | F | None | Respiratory failure from pulmonary adenocarcinoma | |
Control 5 | 58 | M | None | GI hemorrhage and shock from cirrhosis | |
Control 6 | 46 | F | HOCM | Metastatic breast cancer in setting of HOCM-induced heart failure | |
Control 7 | 68 | M | None | Pulmonary squamous cell carcinoma leading to hemorrhage and desanguination | |
Control 8 | 65 | M | CAD | Interstitial lung disease complicated by bronchopneumonia | |
Control 9 | 71 | F | None | ILD leading to pneumonia | |
Control 10 | 62 | F | None | Metastatic breast cancer | |
Control 11 | 68 | M | CAD | Cirrhosis leading to esophageal varices and bleeding | |
Control 12 | 53 | M | CAD | GI bleeding from cirrhosis |
F, female; M, male; ALL, acute lymphoblastic leukemia; ARDS, acute respiratory distress syndrome; CAD, coronary artery disease; CHF, congestive heart failure; CKD, chronic kidney disease; DAD, diffuse alveolar damage; DVT, deep venous thrombosis; GI, gastrointestinal; HOCM, hypertrophic obstructive cardiomyopathy; ILD, interstitial lung disease; MI, myocardial infarction; NSTEMI, non-ST elevation myocardial infarction.
All patients with COVID-19 were positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by RT-PCR.