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. 2022 Jan;192(1):112–120. doi: 10.1016/j.ajpath.2021.09.004

Table 1.

Patient Demographics and Clinical Information

COVID-19 patients (n = 7) Age Sex Cardiac history Medications Cause of death
Patient 1 94 F CAD Remdesivir Pneumonia
Patient 2 65 F CAD, DVT, NSTEMI Prednisone, Rivaroxaban Pneumonia w/DAD leading to ARDS
Patient 3 77 M None Pneumonia and pulmonary thrombosis in setting of end stage renal disease
Patient 4 57 M None Pneumonia leading to cardiac arrest, followed by shock
Patient 5 90 M CAD, stroke Pneumonia w/DAD
Patient 6 68 F CAD, MI Pneumonia in setting of CV disease and recent MI
Patient 7 50 M None Bilnatumomab Pneumonia w/DAD in setting of B cell ALL relapse
Controls (n = 12)
 Control 1 89 M CAD, stroke Atherosclerotic and hypertensive CV disease
 Control 2 47 M CAD, MI CHF
 Control 3 79 M Atrial Flutter, CKD CHF
 Control 4 58 F None Respiratory failure from pulmonary adenocarcinoma
 Control 5 58 M None GI hemorrhage and shock from cirrhosis
 Control 6 46 F HOCM Metastatic breast cancer in setting of HOCM-induced heart failure
 Control 7 68 M None Pulmonary squamous cell carcinoma leading to hemorrhage and desanguination
 Control 8 65 M CAD Interstitial lung disease complicated by bronchopneumonia
 Control 9 71 F None ILD leading to pneumonia
 Control 10 62 F None Metastatic breast cancer
 Control 11 68 M CAD Cirrhosis leading to esophageal varices and bleeding
 Control 12 53 M CAD GI bleeding from cirrhosis

F, female; M, male; ALL, acute lymphoblastic leukemia; ARDS, acute respiratory distress syndrome; CAD, coronary artery disease; CHF, congestive heart failure; CKD, chronic kidney disease; DAD, diffuse alveolar damage; DVT, deep venous thrombosis; GI, gastrointestinal; HOCM, hypertrophic obstructive cardiomyopathy; ILD, interstitial lung disease; MI, myocardial infarction; NSTEMI, non-ST elevation myocardial infarction.

All patients with COVID-19 were positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by RT-PCR.