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. 2012 Nov 14;2012(11):CD006145. doi: 10.1002/14651858.CD006145.pub3

Dimeo 2004.

Study characteristics
Methods RCT; 2 groups, stratified for tumour location
Participants 72 various cancer diagnoses, post anti‐cancer treatment
Interventions Exercise: supervised stationary bike, 30 mins/per session, 5 days/week. 80% HRmax or 13 to 14 on Borg scale.
Control: relaxation training 45 mins, 3 times/week
Both groups lasted 3 weeks
Outcomes HRQOL (including fatigue)
Physical performance
Notes Methodological quality score: 3
Main purpose of exercise: to reduce fatigue severity
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk "Randomisation was carried out using a computer‐generated random number list"
Allocation concealment (selection bias) Low risk "randomisation sequence was concealed until assignment of interventions"
Blinding of outcome assessment (detection bias)
All outcomes High risk Blinding not done
Incomplete outcome data (attrition bias)
All outcomes Unclear risk 3 participants dropped out of the study; unclear if intention‐to‐treat analysis was performed
Selective reporting (reporting bias) Low risk Fatigue outcome reported