Shelton 2009.

Study characteristics
Methods	RCT; 2 groups
Participants	53 patients with leukaemia within 6 months of allogenic stem cell transplant
Interventions	Exercise (supervised): combined aerobic and resistance training 3 times/week for 4 weeks. Individualised, aerobic exercise included upper and lower extremity ergometry and treadmill for at least 20 minutes at 60% to 75% age predicted HRmax. Various resistance exercises, 1 to 3 sets of 10 reps with intensity determined by fatigue. Intensity of aerobic and resistance training increased every third session unless extreme fatigue was reported. Exercise (unsupervised): combined aerobic (walking) and resistance training for 4 weeks. Walking time increased to 30 mins over the 4 weeks. Various resistance exercises 1 to 3 sets of 10 to 15 reps. Intensity of the exercise was not reported.
Outcomes	Fatigue Aerobic capacity Physical performance
Notes	Methodological quality score: 2 Main purpose of exercise: to improve functional outcome
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	"randomly assigned" but method not described
Allocation concealment (selection bias)	Unclear risk	Not stated
Blinding of outcome assessment (detection bias) All outcomes	High risk	Blinding not done
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Unclear
Selective reporting (reporting bias)	Low risk	Fatigue outcome reported