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. 2021 Sep 29;129(9):097011. doi: 10.1289/EHP9424

Figure 1.

Figures 1A, 1B, and 1C are error bar graphs, plotting Adjusted standard deviation difference in bone mineral content z-score per doubling of maternal serum Per- and polyfluoroalkyl substances concentration during gestation (nanogram per milliliter), ranging from negative 0.6 to 0.4 in increments of 0.2 (y-axis) across whole body less head, total hip, femoral neck, forearm, and spine (x-axis) for perfluorooctanoic acid, perfluorononanoic acid, perfluorohexane sulfonic acid, and perfluorooctane sulfonic acid, respectively.

Adjusted associations of maternal serum perfluoroalkyl substances concentrations with BMC z-scores at 12 years of age: The Health Outcomes and Measures of the Environment (HOME) Study. (A) overall (n=206), (B) males (n=93), (C) females (n=113). Difference (95% confidence interval) in BMC z-score per log2 unit increase in perfluoroalkyl substance concentrations estimated in separate linear regression models adjusted for maternal age at delivery, midpregnancy BMI, race/ethnicity, household income, parity, prenatal vitamin use, average blood lead concentration, and child age at follow-up. Models for the overall population are additionally adjusted for child sex and child sex by child age at follow-up. Missing covariate information accounted for using full-information maximum likelihood. Numeric results are reported in Tables S3 and S4. Note: BMC, bone mineral content; BMI, body mass index; PFHxS, perfluorohexane sulfonic acid; PFNA, perfluorononanoic acid; PFOA, perfluorooctanoic acid; PFOS, perfluorooctane sulfonic acid.