Table 1.

Demographic, clinical, and postmortem characteristics of study sample

Characteristics	N=569
Demographic and clinical measures
Age at death, years	90.8 (6.1)
Sex, males (%)	168 (29.5 %)
Education, years	14.8 (2.9)
APOE4 allele carrier (%)	123 (21.6 %)
Late-life cognitive activity, score	2.59 (0.91)
MIND diet, score	7.35 (1.42)
Physical activity, moderate/vigorous-intensity exercise, hours/week	50 (0-180)
Total energy intake, kcal	1831 (534)
Postmortem measures
NIA-Reagan AD (%)	374 (65.7 %)
Global AD pathology	0.72 (0.58)
β-amyloid load	1.70 (1.17)
Tangle density	7.35 (8.19)
Lewy Bodies (%)	136 (24.6 %)
Microinfarcts (%)	211 (37.1 %)
Microinfarcts (%)	178 (31.3 %)
Cerebral atherosclerosis, moderate–severe (%)	135 (23.7 %)
Arteriolosclerosis, moderate–severe (%)	159 (27.9 %)
Cerebral amyloid angiopathy (%)	452 (79.6 %)
TDP-43 pathology in amygdala and beyond (%)	310 (54.7 %)
Hippocampal sclerosis (%)	54 (9.5 %)
Postmortem interval autopsy, hours	9.43 (8.96)

Data is shown as mean (standard deviation), median (interquartile), or number (%)