Table 1.
Characteristics of pediatric bronchial Dieulafoy's disease (BDD).
References | Country | Sex | Age (years) | Respiratory history | Reason for admission | X-ray | CT | Bronchoscopy | Location | Biopsy and hemoptysis | Angiography | Source of vessel | Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ganganah et al. (4) | Japan | Male | 13 | No | Intermittent hemoptysis over a week | NA | Ground glass opacity (GGO) of the right posterior basal lobe | Two elevated lesions with white caps | One at the entrance of the right lateral basal bronchus, one over the subcarina of the right lateral and posterior basal bronchus-black arrows | No biopsy | The right bronchial artery was tortuous and dilated, measuring ~2.7 mm in diameter | BA | BAE (recurred) + surgery (resection of the right middle and lower lobes) |
Fang et al. (5) | China | Male | 13 | No | Massive hemoptysis | NA | Exudative lesion, consolidation, and atelectasis of right lower lobe | Two nonpulsating polypoid nodules of ~3–6 mm | Located at the carina between the external and posterior basal segment of the right lower lobe | No biopsy | A distal right branch of this bronchial artery was dilated and tortuous | BA | Surgery |
Giordano et al. (6) | Italy | Male | 11 | No | Chest discomfort and massive hemoptysis | NA | Diffuse “ground-glass” opacity at the lower lobe of the right lung | NA | At the lower lobe of the right lung | No biopsy | A dilated and tortuous right bronchial artery | BA | BAE |
Woodhull et al. (7) | China | Male | 8 | No | A sudden episode of severe hematemesis | Partial collapse of the right middle and lower lobe | An abnormally dilated right bronchial artery with collapsed right middle and lower lobes, and partial consolidation of the contralateral left lower lobe | Carina, left lower lobe, and lingula revealed minimal fresh and altered blood | At the right lower lobe | No biopsy | NA | BA | BAE |
Yeh et al. (8) | China | Female | 7 | No | Frequent episodes of unprovoked massive hemoptysis for 5 months | NA | An abnormal vascular lesion in her bronchus intermedius | Patchy chronic inflammation in the submucosa and patchy hypertrophy of the subepithelial connective tissue | A polypoid lesion in right bronchus intermedius | No biopsy | Multiple tortuous enlarged feeding vessels | BA | BAE + surgery (a sleeve resection of the bronchus intermedius) |
Niu et al. (9) | China | Female | 8 months | No | Hemoptysis | NA | Flaky blur of the right upper lobe | Rough and erosive endometrium, bleeding | Upper lobe and middle bronchi of the right lung | No biopsy | Tortuous and dilated, beaded bronchial artery | BA | BAE (failed) + surgery (resection of the right upper lobe) |
Chen et al. (this study) | China | Male | 9 months | No | Intermittent hemoptysis | Bronchitis | Ground glass opacity of both lungs | A smooth mucosal protrusion | Opening of the right lower lobe | No biopsy | Distorted bilateral bronchial arteries | BA | BAE |