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Surface tension and contact angle values of the BH solution, Betoptic, and MIDFDS (data expressed as the mean values ± SD, n = 3). 1–6 are one-time measurement results. (a) In vitro cumulative release percentage curve of BH solution, Betoptic, and MIDFDS (n = 3), and SEM images of MIDFDS at 0, 0.5, 4, and 12 h. (b) The drug was released from the core of the microsphere through the pore formed by the swelling of Eudragit in MIDFDS following Fick diffusion without dissolved MIDFDS.
