Figure 6.
TP53-MT affects the efficacy of common BLCA chemotherapeutic agents in GDSC-BLCA cell lines. Ln(IC50) values of gemcitabine (A), doxorubicin (B) and mitomycin C (C) between TP53-MT and TP53-WT cell lines. IC50 s reported in GDSC were loge transformed. The differences in the ln(IC50) values of different drugs between the TP53-MT and TP53-WT cell lines were tested using the Mann-Whitney U test. ns: not significant; *p < 0.05; **p < 0.01; ***p < 0.001.