Figure 1.
RSV and MET intervention and the IPGTT results before and after 8 weeks of being fed the HFD, and insulin sensitivity after RSV and MET treatment. After 8 weeks of high-fat diet. (A) Blood glucose levels at 0, 15, 30, 60 and 120 min after the IPGTT. (B) AUC of glucose. (C) Blood glucose levels at 0, 15, 30, 60 and 120 min after the IPGTT, (D) AUC of glucose, (E) fasting blood glucose levels, (F) fasting blood insulin levels, and (G) QUICKI after 8 weeks of treatment. Data are presented as the mean ± SD (n=10). One-way ANOVA was used for statistical analysis followed by Tukey's or Tamhane's multiple comparison tests. *P<0.05 vs. CON; #P<0.05 vs. HFD; and &P<0.05 vs. HFD + RSV. RSV, resveratrol; MET, metformin; HFD, high-fat diet; IPGTT, intraperitoneal glucose tolerance test; AUC, area under the curve; QUICKI, quantitative insulin sensitivity check index.