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. 2021 Sep 28;48(5):206. doi: 10.3892/ijmm.2021.5039

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Copyright: © Shu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Relative protein expression of PI3K/Akt signaling pathway-related indicators in mouse liver. (A) Protein bands of PI3K-Akt signal pathway molecules; (B) PI3K; (C) p-PI3K/PI3k; (D) Akt; (E) p -Akt/Akt; (F) FOXO1; (G) G6PC; (H) PEPCK. Data are presented as the mean ± SD (n=3). One-way analysis of variance was used for statistical analysis followed by Tukey's or Tamhane's multiple comparison tests. ^*P<0.05 vs. CON; ^#P<0.05 vs. HFD; ^&P<0.05 vs. HFD + RSV. RSV, resveratrol; MET, metformin; HFD, high-fat diet; FOXO1, forkhead box O1; G6PC, glucose-6-phosphatase catalytic subunit 1; PEPCK, phosphoenolpyruvate carboxykinase 1.