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. 2021 Sep 21;97(12):e1229–e1242. doi: 10.1212/WNL.0000000000012513

Figure 2. ROC Curves for Distinguishing Pathology-Confirmed AD Dementia From Non-AD Dementia and Aβ-PET–Negative Healthy Controls.

Figure 2

Receiver operating characteristic (ROC) curves showing the performance of Elecsys CSF biomarkers (A) and plasma biomarkers compared to CSF tau phosphorylated at threonine 181 (p-tau181) (B) for the discrimination of pathology-confirmed Alzheimer disease (AD) dementia from β-amyloid (Aβ)-PET–negative healthy controls (A.a and B. a) and non-AD dementia (A.b and B.b). Areas under the curve (AUC) and 95% confidence interval are reported in the inset of each panel. CN = cognitively normal; NfL = neurofilament light; t-tau = total tau.