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. Author manuscript; available in PMC: 2022 Apr 1.
Published in final edited form as: Radiother Oncol. 2021 Feb 3;157:155–162. doi: 10.1016/j.radonc.2021.01.023

Figure 4.

Figure 4.

Assessment of cardiac morphology and function of irradiated and unirradiated ApoE−/− mice using echocardiogram and pressure-volume loop analysis 12 months after irradiation. (A) Dot plot showing echocardiography measurements of fractional shortening, left ventricular (LV) mass, left ventricular end diastolic diameter (LVDd) and end systolic diameter (LVDs) in unirradiated (n=4) and irradiated (n=10) ApoE−/− mice. (B) Load-dependent LV systolic performance parameters derived from pressure-volume loop analysis of unirradiated (n=4) and irradiated (n=10) ApoE−/− mice. Each dot represents one mouse. (C) Load-dependent LV diastolic performance parameters derived from pressure-volume loop analysis of unirradiated (n=4) and irradiated (n=10) ApoE−/− mice. Each dot represents one mouse. Data are presented as mean ± SEM. *P<0.05 by Mann-Whitney U test.