Table 2:

Common manifestations of liver dysfunction

Organ	Manifestation
Brain	Encephalopathy Increased ICP
Heart	Increased cardiac output from low SVR Low SVR Increased heart rate Low cardiac output if complicated by pulmonary hypertension resulting in right ventricle dysfunction
Lungs	Portopulmonary hypertension Hepatopulmonary syndrome Hydrothorax
GI	Esophageal varices Portal hypertension Ascites
Kidney	Kidney dysfunction Hepatorenal syndrome type 1 (two-fold increase in creatinine with decreased urine output over two weeks and is associated with multi-organ dysfunction in absence of renal pathology)152 Hepatorenal syndrome type 2 (slower decrease in renal function in the absence of other renal pathology)
Hematologic	Thrombocytopenia Prolonged PT/PTT Decreased Antithrombin III

GI: gastro-intestinal; ICP: intracranial pressure; PT: prothrombin time; PTT: partial thromboplastin time; SVR: systemic vascular resistance.