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. 2021 Sep 23;218(11):e20210021. doi: 10.1084/jem.20210021

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© 2021 Lin et al.

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Figure S2. — IL-27 produced by IECs is dispensable for both T-bet⁺ T reg cell differentiation and IL-10 induction in T cells. (A) FACS analysis and frequencies of T-bet⁺ T reg cells in LP of IEC-KO mice and WT littermates (∼10–12 wk). (B) FACS analysis and frequencies of IL-10⁺ T reg cells in LP of IEC-KO mice and WT littermates (∼10–12 wk). Each symbol represents an individual mouse, and the bar represents the mean. Data are pooled from at least three independent experiments. Results of Student’s t test: n.s., not significant.