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. 2021 Sep 29;16(9):e0257253. doi: 10.1371/journal.pone.0257253

Table 6. Multivariate logistic regression analysis of selected treatments associated with AKI development following adjustment with age.

Patients Treatment OR 95% CI P value
Overall Patients
AKI Stage I ACEI/ARBS 1.31 0.62–2.78 n.s.
Furosemide 2.83 1.48–5.41 <0.01
Dexamethasone 3.06 1.48–6.33 <0.01
AKI Stage II+III ACEI/ARBS 0.27 0.10–0.73 <0.01
Furosemide 4.83 2.51–9.26 <0.001
Dexamethasone 2.76 1.32–5.79 <0.01
Non-AKI Ref Ref Ref
Hypertensive
AKI Stage I ACEI/ARBS 0.73 0.25–2.14 n.s.
Furosemide 2.83 1.48–5.41 <0.01
Dexamethasone 4.56 1.25–16.52 <0.01
AKI Stage II+III ACEI/ARBS 0.19 0.05–0.19 <0.05
Furosemide 7.98 2.58–24.73 <0.001
Dexamethasone 2.76 1.32–5.79 <0.05
Non-AKI Ref Ref Ref
Diabetic
AKI Stage I ACEI/ARBS 0.81 0.29–2.28 n.s.
Furosemide 4.06 1.55–10.63 <0.01
Dexamethasone 2.09 0.71–6.14 n.s.
AKI Stage II+III ACEI/ARBS 0.19 0.05–0.19 <0.01
Furosemide 7.49 2.71–20.69 <0.001
Dexamethasone 2.24 0.72–6.95 n.s.
Non-AKI Ref Ref Ref