Table 1.
Clinicopathologic features of 9 patients with breast implant associated anaplastic large cell lymphoma.
| Patient | Age | Reason for Implant | Type of Implant | Number of Years after Implant | Presentation | Stage | Treatment | pSTAT IHC |
|---|---|---|---|---|---|---|---|---|
| 1 | 68 | IDC | Textured | 8 | Left breast swelling | T2 | Bilateral complete capsulectomies | Positive |
| 2 | 77 | IDC | Textured | 12 | Right breast mass | T4, stage IIA | Excision and complete capsulectomy | Positive |
| 3 | 61 | IDC and ILC | Textured | 8 | Right breast swelling, effusion | T1* | Bilateral complete capsulectomies | N/A |
| 4 |
58 | DCIS | Textured | 6 | Firmness above her left breast implant and change in shape of implant | T4N2M0 | Capsulectomy and BV-CHP x 6 cycles + consolidative radiotherapy (3060 cGY in 17 fractions) | Positive |
| 5 | 65 | IDC | Textured | 10 | Right breast effusion | T1* | Complete capsulectomy | Positive |
| 6 | 35 | Cosmetic | Textured | 8 | Right breast swelling, effusion | T1 | Bilateral complete capsulectomies | N/A |
| 7 | 51 | IDC | Textured | 6 | Left breast swelling, effusion | T1, stage IA | Bilateral complete capsulectomies | Positive |
| 8 | 66 | IDC | Textured | 11 | Cutaneous lesion | T4 | XRT (15 fractions, total 3000cGY)-, 6 cycles BV-CHOP, SCT | Negative |
| 9 | 50 | ILC | Textured | 6 | Left breast swelling, fevers, night sweats | T3, stage 1C | Bilateral complete capsulectomies | Positive |
IDC, invasive ductal carcinoma; ILC, invasive lobular carcinoma; DCIS, ductal carcinoma in situ; SCT, stem cell transplant; IHC, Immunohistochemistry;
*
lymphoma confined to fluid only