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. 2021 Sep 29;398(10307):1230–1238. doi: 10.1016/S0140-6736(21)01960-7

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Relative risk of mortality at early-adopting centres (on or before May 1 and after May 1) and at late-adopting centres (after May 1)

Group A1 patients started ECMO on or before May 1, 2020, at early-adopting centres. Group A2 patients started ECMO between May 2 and Dec 31, 2020, at early-adopting centres. Group B patients received ECMO at late-adopting centres, which only provided ECMO for COVID-19 after May 1, 2020. BMI=body-mass index. ECMO=extracorporeal membrane oxygenation. PaCO₂=partial pressure of arterial carbon dioxide. PaO₂:FiO₂=ratio of the partial pressure of arterial oxygen to the fraction of inspired oxygen. VA=venoarterial. VV=venovenous. VVA=veno-venoarterial. *Chronic respiratory disease is a pre-ECMO comorbidity.