Skip to main content
. 2021 Sep 29;10:e72104. doi: 10.7554/eLife.72104

Figure 1. Debated models of the cell cycle.

Figure 1.

Left diagram depicts the long-standing model of cell cycle regulation where cellular events are triggered directly by the principal cyclin-dependent kinase (Cdk)/cyclin cell division oscillator (CCO). Right diagram describes the emerging concept of autonomous clocks, where the CCO phase-locks the rhythms of otherwise intrinsic mechanisms responsible for timing different cellular events.