Fig. 1.

FABPRO-GI development process. CDI cognitive debriefing interview, CEI concept elicitation interviews, FABPRO-GI FABry disease Patient-Reported Outcome-Gastrointestinal, GI gastrointestinal; h hour. ^aArticles identified in the literature review were considered relevant if they focused primarily on the GI symptoms of Fabry disease. Articles were excluded if they focused primarily on the pathogenesis, genetics, or molecular histology of Fabry disease; focused primarily on non-GI symptoms of Fabry disease; or discussed solely Fabry disease in a population <16 years of age