Table 2.

Poisson regression models of the association of selected factors with the ARR during the study observation period

Parameter	Category vs reference	ARRR	p value
Univariable Poisson regression analysis
Sex	Male vs female	0.861	0.557
Age at baseline (years)	≤ 40 vs > 40	1.082	0.753
Disease duration at baseline (years)	≤ 5 vs > 5	0.787	0.333
Number of relapses in the year prior to baseline	≤ 1 vs > 1	0.377	< 0.001
Number of prior DMTs	≤ 1 vs ≥ 2	0.546	0.008
Baseline EDSS	≤ 3 vs > 3	0.900	0.677
Multivariable Poisson regression analysis; 299 observations
Sex	Male vs female	0.846	0.463
Disease duration at baseline (years)	≤ 5 vs > 5	0.826	0.388
Number of relapses in the year prior to baseline	≤ 1 vs > 1	0.356	< 0.001
Number of prior DMTs	≤ 1 vs ≥ 2	0.535	0.004

ARRR annualized relapse rate ratio, DMT disease-modifying therapy, EDSS expanded disability status scale