In patients with relapsing-remitting multiple sclerosis (RRMS) treated with natalizumab in routine care setting in Greece, natalizumab yielded long-term benefits in terms of lowering the number of relapses and reducing disability progression.

The results of TOPICS Greece complement previous studies, indicating that natalizumab is a highly effective treatment for RRMS with an expected list of serious adverse events, thus, supporting its use, under the recommended risk minimization measures, for patients with highly active disease.