Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 29;11:19296. doi: 10.1038/s41598-021-98590-9

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

GABA_BR deficiency in striatum neurons increases expression of cFos + /drd1 + cells in CPu neurons. (A and C) Representative photographs showing the staining of cFos (green), dopamine receptor d1 (drd1) (red), and DAPI (blue) in the caudate putamen (CPu) (A) and nucleus accumbens (NAc) (C) of wild-type (WT) and knockout (KO) mice in the binge group. White arrowheads show the colocalization of cFos and drd1. Scale bars: 50 μm. (B and D) cFos-positive cells in drd1-positive neurons (cFos + /drd1 +) in the CPu (B) and NAc (D) of WT and KO mice in the binge group. All values are mean ± SEM. Statistical analyses were performed using two-way factorial analysis of variance (ANOVA) followed by Sidak’s post-hoc test (B and D). ns: not significant. #p < 0.05 versus 0 min in WT mice. †p < 0.05 versus 0 min in KO mice. *p < 0.05 versus WT mice. See also Supplemental Table 2 for details on statistics.