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. 2021 Sep 29;11:19296. doi: 10.1038/s41598-021-98590-9

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Schematic of role of GABA_BR signaling in striatum in suppression of binge-like consumption of a HFD. We suggest that gamma-aminobutyric acid type B receptor (GABA_BR) signaling in the caudate putamen (CPu) suppresses the binge-like consumption of a high fat diet (HFD) by inhibiting downstream of dopamine receptor d1 (drd1) signaling in the CPu. The figure image was drawn using PowerPoint 2017 (Microsoft, USA).