Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 29;12(10):888. doi: 10.1038/s41419-021-04193-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 4 — A RNA-seq analysis revealed the top 23 differentially expressed genes after the depletion of hsa_circ_0043280 in MS751 and SiHa cells. B PAQR3 mRNA and protein expression levels were analyzed by qRT-PCR and western blotting after hsa_circ_0043280 overexpression (left) or ablation (right). C Expression levels of PAQR3 in CCa tissues in comparison with normal tissues, as determined by qRT-PCR. D Scatter plot analysis of the correlation between mRNA expression levels of hsa_circ_0043280 and PAQR3 in 40 fresh cervical cancer tissues. E, F Cell proliferation ability was detected by CCK-8 and EdU assays in the indicated cells. Original magnification, × 100. G Cell migration abilities were measured by wound healing assays in the indicated cells. Original magnification, × 100. H Transwell assays were used to detect the migration and invasion capabilities of the indicated cells. Original magnification, × 100. I Western blot analysis of the protein levels of several EMT markers Snail, E-cadherin, N-cadherin and Vimentin, p-ERK, and p-AKT, in the indicated cells. Each experiment was performed at least three times independently. **P < 0.01; ***P < 0.001.