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. 2021 Sep 29;12(10):888. doi: 10.1038/s41419-021-04193-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — A The proliferative abilities of MS751 and HeLa cells were detected by EdU assays in the indicated cells. Original magnification, × 100. B, C Transwell assays were performed to investigate the migration and invasion abilities of MS751 and HeLa cell lines in the indicated groups. Original magnification, × 100. D Western blot analysis of the protein levels of various EMT markers Snail, E-cadherin, N-cadherin and Vimentin, p-ERK, and p-AKT in the indicated cells. E Schematic illustrating the hsa_circ_0043280/miR-203a-3p/PAQR3 signaling pathways in CCa. Hsa_circ_0043280 regulates the expression of PAQR3 by sponging miR-203a-3p and repressing the tumor growth and metastasis of CCa. Each experiment was performed at least three times independently. **P < 0.01; ***P < 0.001.