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. 2021 Sep 29;7:267. doi: 10.1038/s41420-021-00656-0

Table 3.

Hemodynamic parameters at baseline after 2 h of reperfusion.

HR (bmp) LVSP (mm Hg) +dp/dt (mm Hg/s) dp/dt (mm Hg/s)
NS 351 ± 24 119 ± 10 6379 ± 575 4659 ± 391
DS 310 ± 16a 103 ± 10a 5309 ± 380a 3538 ± 341a
10 min Before ischemia (baseline)
 I/R 356 ± 21 122 ± 9 6423 ± 559 4721 ± 415
 DIR 311 ± 14b 105 ± 11b 5320 ± 296b 3578 ± 339b
 DIR + 5-aza-CdR 315 ± 18 106 ± 9 5354 ± 408 3587 ± 254
2 h After reperfusion
 I/R 299 ± 20a,c 98 ± 6a,c 4619 ± 369a,c 3179 ± 240a,c
 DIR 226 ± 14a–c 81 ± 7a–c 2589 ± 213a–c 2004 ± 182a–c
 DIR + 5-aza-CdR 244 ± 10c,d 90 ± 6c,d 3626 ± 305c,d 2798 ± 254c,d

Results are expressed as mean ± SD, n = 8.

DIR diabetes mellitus + I/R, DIR+5-aza-CdR diabetes mellitus + I/R + 5-aza-CdR, DS diabetes mellitus + sham, HR heart rate, I/R ischemia/reperfusion, LVSP left ventricular systolic pressure, NS normal + sham.

aP < 0.05 vs. NS group.

bP < 0.05 vs. their corresponding I/R group.

cP < 0.05 vs. their corresponding baseline.

dP < 0.05 vs. their corresponding DIR group.