Table 10.

Association between DHE exposure before or during pregnancy and the risk of spontaneous abortion by categories of DHE exposure.

Characteristics	Spontaneous abortion
	Cases n = 29,104	Controls n = 287,607	Crude OR (95% CI)	Adjusted OR (95% CI)
	n (%)
Study medication exposure during the pregnancy
DHEa prior to pregnancy only	12 (0.04)	83 (0.03)	1.28 (0.91–1.80)	1.27 (0.89–1.81)
DHE prior and during pregnancy	18 (0.06)	68 (0.02)	3.12 (1.01–9.64)	2.71 (0.81–9.07)
DHE during pregnancy only	4 (0.01)	82 (0.03)	0.39 (0.11–1.38)	0.46 (0.13–1.63)

Adjusted for all variables included in Table 6.

^aDihydroergotamine.